Circrhobtb3

Author: adrd

August undefined, 2024

WebMar 20, 2024 · CircRHOBTB3 interacted with the RNA-binding protein, IGF2BP3, to stabilize its expression in CC cells and is putatively transcriptionally regulated by NR1H4. WebDec 1, 2024 · The molecular mechanism of circRHOBTB3 inhibits the proliferation and invasion of epithelial ovarian cancer by serving as the ceRNA of miR-23a-3p Article Full-text available Jun 2024 Yihan Fu...

National Center for Biotechnology Information

WebJun 2, 2024 · The molecular mechanism of circRHOBTB3 inhibits the proliferation and invasion of epithelial ovarian cancer by serving as the ceRNA of miR-23a-3p Rising evidences bespeak that circular RNAs are indispensable in regulating cellular biological behaviors and engaging in diseases' occurrence. WebJun 1, 2024 · Results: We identified circRHOBTB3 which is markedly downregulated in CRC tissues and cell lines. Furthermore, lower circRHOBTB3 levels were significantly … canadian pediatric society anaphylaxis

NR1H4-mediated circRHOBTB3 modulates the proliferation

WebSep 9, 2024 · Chen C, Yu H, Han F, Lai X, Ye K, Lei S, et al. Tumor-suppressive circRHOBTB3 is excreted out of cells via exosome to sustain colorectal cancer cell fitness. Mol Cancer. 2024;21:46. WebJun 1, 2024 · CircRHOBTB3 has been reported to participate intimately in the progression of some cancers. Nevertheless, the mechanism by which circRHOBTB3 regulates … WebOverexpression of circRHOBTB3 suppresses tumor metastasis in CRC cells. Mechanistically, circRHOBTB3 binds to HuR, which is a ubiquitously expressed and … fisher irrigation and lighting

Circular RNA circRHOBTB3 acts as a sponge for miR-654-3p …

Tumor-suppressive circRHOBTB3 is excreted out of cells via …

WebFigure Legend Snippet: CircRHOBTB3 is down-regulated in EOC. A Schematic illustration showing the circularization of RHOBTB3 exon 6 and exon 7 forming circRHOBTB3. B Relative expression of circRHOBTB3 in OC cell lines compared with IOSE-80 was measured by qRT-PCR. C The existence of circRHOBTB3 was validated by RT–PCR … fisher irrigation consultantsWebZestimate® Home Value: $329,501. 103 S Brownthrush Cir, Wichita, KS is a single family home that contains 2,848 sq ft and was built in 1994. It contains 4 bedrooms and 3 … fisher irrigation class

"WebMechanistically, circRHOBTB3 binds to HuR, which is a ubiquitously expressed and functional RNA-binding protein (RBP) in CRC development, and promotes β-Trcp1-mediated ubiquitination of HuR. Normally, HuR binds to the 3'UTR of target mRNAs to facilitate their stabilization, whereas the interaction between circRHOBTB3 and HuR degrades HuR to ... " - Circrhobtb3

Circrhobtb3

WebOct 9, 2024 · By using microarray analysis and statistical methods, Franz et al. have demonstrated that circRHOBTB3 could act as a diagnostic and prognostic biomarker of clear cell renal cell carcinoma . Besides, it was reported that circFAM13B was decreased in the epithelial ovarian cancer specimens, whereas the specific regulatory mechanism … Web3" Wheel-to-Wheel Black Powder Coat Round Tube Steps (53-484-B) by Iron Cross®, 1 Pair. Make getting in and out of your truck easier and improve its looks at the same time. …

Did you know?

WebAmong them, 6 circRNAs (circBNC2, circEXOC6B, circFAM13B, circN4BP2L2, circRHOBTB3 and circCELSR1) have been associated with various clinicopathological features of epithelial ovarian cancer (EOC). More importantly, circEXOC6B and circN4BP2L2 may act as novel diagnostic biomarkers in patients with EOC . Another … Webdetecting both circRHOBTB3 and RHOBTB3 (Fig. 1D). en, the specic back-splicing site of circRHOBTB3 was identied by RT-PCR and Sanger sequencing (Fig. 1E). Compared with the linear host genes RHOBTB3 and GAPDH, circRHOBTB3 signicantly resisted RNase R treatment (Fig. 1F). en, we detected the expres-sion of circRHOBTB3 in serum from 18 …

WebFor instance, EIF4A3 can induce the expression of circMMP9 and circASAP1, 51, 52 FUS can induce abnormally high expression of circRHOBTB3 and circ_002136 in tumors. 53, 54 Through analysis of the Circular RNA Interactome online database, 55 we found that EIF4A3 and FUS contain binding sites WebApr 13, 2024 · Background Osteoarthritis (OA) is the most prevalent age-related disease in the world. Chondrocytes undergo an age-dependent decline in their proliferation and synthetic capacity, which is the main cause of OA development. However, the intrinsic mechanism of chondrocyte senescence is still unclear. This study aimed to investigate …

WebFeb 11, 2024 · circRHOBTB3 is secreted outside of tumor cells and suppresses CRC cells in vitro and in vivo. (A) Expression of circRHOBTB3 in CRC or normal colonic epithelial … WebMar 20, 2024 · CircRHOBTB3 expression is upregulated in CC cells, and circRHOBTB3 knockdown repressed CC cell proliferation, migration, and invasion. Furthermore, …

WebNR1H4-mediated circRHOBTB3 modulates the proliferation, metastasis, and Warburg effects of cervical cancer through interacting with IGF2BP3 Mol Cell Biochem. 2024 Mar 20. doi: 10.1007/s11010-023-04692-5. Online ahead of print. Authors Ailing Ren # 1 , Fan Gong # 2 , Guokun Liu 3 , Wenli Fan 4 Affiliations

WebcircRHOBTB3是通过宿主基因RHOBTB3的剪接和环化产生的。作为Rho GTPase家族的ATPase，宿主基因RHOBTB3参与膜转运和蛋白酶体降解，可通过促进肾癌中HIF-α的蛋白酶体降解来抑制肿瘤生长。先前的研究还表明circRHOBTB3在卵巢癌、胃癌、CRC和肝细胞癌（HCC）中是一种肿瘤抑制性circRNA。然而，其环化模式和外泌体分泌途径尚不明 … fisher irrigation warringtonWebIn a first step, eight circRNAs (circATXN10, circCRIM1, circCSNK1G3, circGUCY1A2, more »... cLPP, circNEAT1, circRHOBTB3, and circSTIL) were identified as differentially expressed via a genome-wide circRNA-based microarray analysis of six PCa samples. Additional bioinformatics and literature data were applied for this selection process. canadian peas for pigeonsWebThe Crossword Solver found 20 answers to "Heartthrob?", 5 letters crossword clue. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. … canadian peak whisky reviewsWebFeb 11, 2024 · Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer Jiaxin Chen, Yizheng Wu, +9 authors Zhangfa Song Biology, Medicine Theranostics 2024 TLDR Findings indicate that circRHOBTB3 exerts suppressive effects on CRC aggressiveness through the … fisher irrigation training classesWebCircRHOBTB3 was downregulated in ovarian cancer tissues and cells. RESULTS: Functionally, circRHOBTB3 overexpression could markedly suppress cell proliferation, metastasis and glycolysis, whereas the opposite results could be observed in the deletion of circRHOBTB3. Additionally, xenograft experiment also identified the above results. canadian pediatric society cmvWebJan 13, 2024 · Taken together, this study revealed that circRHOBTB3 might function as competing endogenous RNA (ceRNA) for miR-654-3p, which could contribute to growth … fisher irwinWebJul 30, 2024 · Circular RNAs (circRNAs) have emerged as significant regulators in human cancers. We aimed to explore the functional role of circular RNA RHOBTB3 (circRHOBTB3) in ovarian cancer. The expression of circRHOBTB3 was detected by real-time quantitative PCR (RT-qPCR). canadian pediatric society swaddling