Ephrin-a4

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August undefined, 2024

http://www.cnreagent.com/show1001180/product_93758.html WebRecombinant Human Ephrin A4 protein (His tag) is a HEK 293 Full length protein 26 to 171 aa range, > 95% purity, < 1.000 Eu/µg endotoxin level and validated in SDS-PAGE.

Human ribonuclease 1 serves as a secretory ligand of ephrin A4 ... - PubMed

WebNov 16, 2024 · Citation 4 In particular, the ephrin A4 receptor (EphA4) was expressed in the reactive astrocytes in mice and human brain tissue after spinal cord hemisection Citation 5, Citation 6 and traumatic brain injury, Citation 7 respectively. Moreover, deleting or blocking EphA4 in mice or rats with spinal cord injury promoted axonal regeneration and ... WebMay 16, 2016 · Using fluorescence in situ hybridization, Cerretti et al. (1996) mapped the EPLG4 gene to a cluster on chromosome 1q21-q22, together with EPLG1 (EFNA1; 191164) and EPLG3 (EFNA3; 601381 ). By interspecific backcross analysis, they mapped the mouse EPLG4 homolog (Epl4) to the central region of mouse chromosome 3. slow pitch jigging reels for sale

Anti-Ephrin A4 Antibodies Invitrogen

WebJan 12, 2024 · Among EPHA10 ligands, exogenous ephrin A4 (EFNA4) induced the most OSCC cell migration and sphere formation, as well as up-regulation of SNAIL, NANOG, and OCT4. These effects were abolished by ... Ephrin A4 is a protein that in humans is encoded by the EFNA4 gene. This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structure… Web0.1ml EphA1/Ephrina1/Ephrin A1 Receptor 内皮细胞受体蛋白酪氨酸激酶A抗体（肿瘤坏死因子α诱导蛋白4） 96T/48T 0.1ml EphA4 酪氨酸蛋白激酶A4抗体 96T/48T 0.1ml Ephrin B Ephrin B抗体 96T/48T 0.1ml phospho-Ephrin B(Tyr329) 磷酸化Ephrin B抗体 96T/48T slow pitch jigging seminar

Ephrin A4 Protein, Human, Recombinant (His Tag)

Ephrin A4 - an overview ScienceDirect Topics

WebJan 12, 2024 · Ephrin type-A receptor 10 (EPHA10) has been implicated as a potential target for breast and prostate cancer therapy. However, its involvement in oral squamous … WebEPH-related receptor tyrosine kinase ligand 4 (Ephrin-A4) also known as EFNA4, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). slow pitch jig moldWebEphrin-A4 binds EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, and EphB1. To date, at least 14 members of the Eph receptor family and a family of 8 ligands have been identified. Ligands of Eph family receptors are structurally related membrane-bound proteins that can be subdivided into two major subclasses: ephrin-A and ephrin-B. Ligands in the ... slow pitch jigging rods australia

"WebJan 5, 2024 · Data show the effects of genetic loss of ephrin-A5, Eph receptors EphA4, and EphA7 on the development of medulloblastoma tumors in the smoothened (Smo) transgenic mouse model. EphA4 mediates long-term contextual fear conditioning memory formation in a kinase-independent manner. with an fibroblast growth factor signal, contributes to … " - Ephrin-a4

Ephrin-a4

WebMar 22, 2024 · Treatment with Ephrin A1-Fc (EA1-Fc) in a mouse model of myocardial infarction (MI) was shown to alter expression of five Ephrin receptors (EphA1-A4 and EphA6) as well as endogenous EA1 ligand when compared to the vehicle treated MI group. Canonical ephrin signaling regulates a wide-variety of physiological processes. WebEphrin A4 is also known as LERK-4 or ELF-4. Ephrin-A4 binds EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, and EphB1. To date, at least 14 members of the Eph receptor family and a family of 8 ligands have been identified. Ligands of Eph family receptors are structurally related membrane-bound proteins that can be subdivided into two major …

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WebThe ephrin receptor A4 (EphA4) is one of the receptors in the ephrin system that plays a pivotal role in a variety of cell-cell interactions, mostly studied during development. In addition, EphA4 has been found to play a role in cancer biology as well as in the pathogenesis of several neurological disorders such as stroke, spinal cord injury, multiple … WebEPH-related receptor tyrosine kinase ligand 4 (Ephrin-A4) also known as EFNA4, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are …

WebSep 15, 2015 · Gene expression analysis of TIC led to the identification of Ephrin-A4 (EFNA4) as a prospective therapeutic target. An ADC comprising a humanized anti-EFNA4 monoclonal antibody conjugated to the DNA-damaging agent calicheamicin achieved sustained tumor regressions in both TNBC and ovarian cancer PDX in vivo. Non-claudin … WebMay 13, 2024 · Notably, ephrin A4 (EphA4) is upregulated in breast cancer stem-like cells (CSCs), and EphA4-mediated juxtacrine signaling …

WebEphrin-A4 (EFNA4) is also known as EPH-related receptor tyrosine kinase ligand 4 (LERK4), EPLG4, which belongs to the ephrin family. EFNA4 contains one ephrin RBD … WebAug 15, 2002 · Methods: Ephrin-A1, ephrin-A3, ephrin-A4, ephrin-A5, ephrin-B1, ephrin-B2, and ephrin-B3 mRNA expression was examined by reverse transcription polymerase chain reaction analysis in nine specimens of human osteosarcoma tissue and five human osteosarcoma cell lines. Ephrin-B1 protein expression was detected …

WebEphrin-A4 was detected in immersion fixed paraffin-embedded sections of human squamous cell carcinoma using Mouse Anti-Human Ephrin-A4 Monoclonal Antibody (Catalog # MAB3692) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Tissue was …

Webephrin-A4, eph-related receptor tyrosine kinase ligand 4, ligand of eph-related kinase 4 GeneRIFs: Gene References Into Functions Interference of EFNA4 suppresses cell … software to open shapefilesWebEphrin-A4, also known as LERK-4 and EFL-4, (1) is a member of the ephrin ligand family which binds members of the Eph receptor family. All ligands share a conserved … slow pitch jigging rods top 10WebThe Ephrin-Ephrin receptor (Eph receptor) system mediates direct cell-to-cell communication through the interaction of the transmembrane proteins Ephrin with the … software to open php fileWebRG express pro-angiogenic CXCL12, vascular endothelial growth factor (VEGF), and Ephrin-A4 (EphA4), which respectively interact with CXCR4, VEGF-receptor-2 … software to open iso filesWebPF-06647263 is a humanized monoclonal antibody against ephrin-A4 conjugated with the cytotoxic agent calicheamicin. Ephrin-A4 was selected as a pharmacological target because it is highly expressed in triple negative breast cancer (TNBC) and ovarian cancer, and it was identified as a novel tumor initiating cell marker. software to open large xml filesWebEphrin receptors (Ephs) are receptor tyrosine kinases (RTKs) implicated in tissue development and homeostasis, and they are aberrantly expressed in tumors. Here, immunohistochemical Eph type-A and -B expression in thymic epithelial tumors (TETs) was assessed and correlated with clinicopathological parameters. Tissue microarrays from 98 … software to open pdf filesEphrins (also known as ephrin ligands or Eph family receptor interacting proteins) are a family of proteins that serve as the ligands of the Eph receptor. Eph receptors in turn compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Since ephrin ligands (ephrins) and Eph receptors … See more Ephrin ligands are divided into two subclasses of ephrin-A and ephrin-B based on their structure and linkage to the cell membrane. Ephrin-As are anchored to the membrane by a Of the eight ephrins … See more Axon guidance During the development of the central nervous system Eph/ephrin signaling plays a critical role in the cell–cell mediated migration of several types of neuronal axons to their target destinations. Eph/ephrin … See more software to open sql database file