WebDrugs interacting with grapefruit and inducing serious clinical consequences (confirmed or very probable) include: immunosuppressants, some statins, benzodiazepines, most calcium channel blockers, indinavir and carbamazepine. There are large inter-individual differences in enzyme efficiency. WebGrapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. The result: too much drug in your body ...
Which Medications Interact With Grapefruit Juice? - Verywell Health
WebMar 7, 2014 · One whole grapefruit, or 200ml of juice, can be enough to cause significant interaction with enzyme activity. The side effects can vary depending on the drug being taken, but can potentially include kidney … WebFeb 16, 2024 · Compounds in grapefruit and grapefruit juice can interact with statins. In extreme cases, this may lead to rhabdomyolysis and even death, but this is rare. The degree of interaction depends on ... small fire ants
Grapefruit: MedlinePlus Supplements
WebDec 9, 2024 · This citrus fruit can affect the enzyme necessary for the drug’s metabolism. As a result, the levels of the main active ingredient could increase and thereby make you more prone to side effects. Men who take Flomax should avoid eating grapefruit and other citrus fruits to prevent drug interaction. WebNov 25, 2024 · Grapefruit contains a compound called furanocoumarin which inhibits a vital enzyme in the small intestine responsible for breaking down nearly half of all medicines. Many drugs are broken down with the help of a vital enzyme called CYP3A4 in the small intestine. The furanocoumarins within grapefruit frequently block the action of CYP3A4. WebGrapefruit juice interacts with some calcium channel blockers and increases the level of the medicine in your blood. If you're taking any of the medicines below, seek advice from your pharmacist or doctor if you wish to include grapefruit or grapefruit juice in your diet. amlodipine felodipine lacidipine lercanidipine nicardipine nifedipine small firearm crossword clue