WebJournal of Chromatography A. Volume 1498, 19 May 2024, Pages 163-168. Development of a dose assay for a Clostridium difficile vaccine using a tandem ion exchange high performance liquid chromatography method. Author links open overlay panel Feng Wang, Sha Ha, Richard R. Rustandi. Show more. Add to Mendeley. Share. WebSep 5, 2024 · High-performance liquid chromatography (HPLC) is a technique in analytical chemistry used to separate the components in a mixture, and to identify and quantify …
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WebIon-exclusion chromatography. Ion-exclusion chromatography is defined [91] as a technique used to separate weak acids, amino acids, sugars, alcohols and other substances on an ion-exchange column. Because of Donnan exclusion, ionic material is excluded from the ion-exchange resin and passes quickly through the column. WebSize exclusion, ion-exchange chromatography (IEC), ion-pair reversed-phase high performance liquid chromatography (IP RP HPLC) and HILIC are the most commonly used modes [1,10,11]. Fig. 3 presents the schematic illustration of the main interactions taking place between oligonucleotides and stationary phase surfaces during a chromatographic … iqbal bhinder surety
Size-exclusion chromatography - Wikipedia
WebHigh-Performance Anion Exchange (HPAE) chromatography is used to separate analytes that are ionized under high pH conditions, such as carbohydrates (pKas are usually between 12-13). This is accomplished through hydroxide-based eluents and a strong anion-exchange stationary phase. WebAug 7, 1998 · Separations are often by size, ion exchange, or hydrophobic-hydrophilic properties of the support, eluent and protein. Adsorption of a protein to a synthetic surface plays an essential role in this complex process. ... In this study … High-performance ion-exchange chromatography and adsorption of plasma proteins J Chromatogr A. 1998 Aug … WebIon exchange chromatography Ion exchange chromatography is probably the most frequently used and versatile method for fractionating biological substances, even proteins and peptides with small differences in charge can be separated. Furthermore, binding and elution conditions are easy to optimize, resulting in fast, high-resolution iqbal broadway housing society